Root 66

Full suite of classic, curated and high-quality medical marijuana products. Strategically placed locations throughout St. Louis area to provide easy access to wide range of products

Root 66 is a locally owned cannabis dispensary chain based in the St. Louis area, and this directory lists 6 of its stores across Missouri and Oklahoma. Its Missouri stores include South Grand in St. Louis, which was the first medical marijuana dispensary to open in the city, along with Dogtown, Des Peres and St. Peters in St. Charles County. The stores serve both adult-use customers 21 and older and Missouri medical card holders.

Menus cover flower, vapes, concentrates, edibles and cannabis beverages, including the chain's in-house Ostara and Cubano brands. The Dogtown store has a drive-thru, and the St. Peters store runs a walk-up window for overnight pickup. Every location has an ATM, and payment is by cash, debit or Dutchie Pay, since credit cards are not accepted. The Road Crew rewards program earns points on each purchase, tracked in the Root 66 app. On arrival, a front-desk associate checks ID before shoppers move to a waiting area with digital menu screens, and budtenders can take time with medical patients across more than one visit if needed.